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Published on: October 24, 2017
Medical options for early pregnancy termination
1Department of Family Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
American Family Physician
|August 1, 1997
Summary
Newly developed medication abortion protocols using methotrexate and misoprostol are highly effective for early pregnancy termination. While side effects like cramping and bleeding occur, these methods are well-tolerated and acceptable to patients.
Area of Science:
- Reproductive Health
- Pharmacology
Background:
- Medication abortion offers a non-invasive option for early pregnancy termination.
- Established protocols are crucial for patient safety and efficacy.
Purpose of the Study:
- To evaluate the effectiveness and tolerability of new medication abortion protocols.
- To compare methotrexate/misoprostol with upcoming mifepristone/misoprostol regimens.
Main Methods:
- Review of newly developed protocols utilizing methotrexate and misoprostol.
- Analysis of efficacy rates for pregnancies under seven weeks gestation.
- Assessment of side effects and patient acceptance.
Main Results:
- Methotrexate and misoprostol protocols demonstrate over 90% efficacy in terminating early pregnancies.
- Common side effects include cramping and bleeding; some women experience prolonged waiting periods.
- Both regimens were generally well-tolerated and acceptable to patients.
Conclusions:
- Newly developed medication abortion regimens using methotrexate and misoprostol are highly effective and well-tolerated.
- Mifepristone combined with misoprostol is also highly effective (94-99%) for early pregnancy termination.
- These pharmacological approaches represent safe and acceptable options for early abortion care.
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