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Related Experiment Videos

Sezary cell-like leukemia with atypical immunophenotype

M Orero, A Miguel-Sosa, A Miguel-Garcia

    Leukemia
    |August 1, 1997
    PubMed
    Summary

    This study details a rare Sezary cell-like leukemia case presenting with anemia and thrombocytopenia, lacking typical T-cell markers but showing clonal T-cell receptor gene rearrangement. The patient achieved remission with chemotherapy.

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    T-Cell Membrane CD45RA (2H4) and CD45RO (UCHL1) Determinants: II, Aberrant HLA-ABC Expression by CD45RA and CD45RO Cell Subpopulations of Mature CD4(+) T-Cell Leukaemias.

    Leukemia & lymphoma·2016

    Area of Science:

    • Hematology
    • Oncology
    • Immunology

    Background:

    • Sezary cell-like leukemia is a rare T-cell neoplasm.
    • Aberrant immunophenotypes are uncommon in primary T-cell leukemias.