Combinatorial protein design: strategies for screening protein libraries
1Division of Chemistry and Chemical Engineering 210-41 California Institute of Technology, Pasadena 91125, USA.
Current Opinion in Structural Biology
|August 1, 1997
Abstract:
Powerful strategies for screening protein libraries further strengthen the arguments for applying 'irrational' approaches to understanding and designing new proteins. Developments during the past year include the application of functional complementation and automation to reduce screening loads, as well as the use of computerized data acquisition to characterize whole protein libraries rather than just selected individuals.
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