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Related Experiment Videos

Measuring column void volumes with NMR

T W Perkins1, T W Root, E N Lightfoot

  • 1Department of Chemical Engineering, University of Wisconsin--Madison 53706, USA.

Analytical Chemistry
|August 15, 1997
PubMed
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A new fluorine Nuclear Magnetic Resonance (NMR) method measures resin porosities and column void volumes without packed columns. This technique characterizes pore size distribution, offering an alternative to chromatography.

Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Nuclear Magnetic Resonance Spectroscopy

Background:

  • Characterizing resin porosity and column void volumes is crucial for chromatography and material science.
  • Existing methods like size exclusion chromatography require packed columns and can be time-consuming.
  • Nuclear Magnetic Resonance (NMR) has not been previously developed for in situ resin porosity measurements.

Purpose of the Study:

  • To develop and demonstrate a novel fluorine NMR method for measuring resin porosities and column void volumes.
  • To characterize the pore size distribution of various media using this new technique.
  • To provide a method that does not require packed columns, unlike traditional chromatographic approaches.

Main Methods:

  • Utilized in situ measurements of void volumes accessible to fluorinated probe molecules.

Related Experiment Videos

  • Employed fluorine Nuclear Magnetic Resonance (NMR) spectroscopy.
  • Applied the procedure to a commercially packed column and several bulk resins.

    • Main Results:

    • Successfully measured resin porosities and column void volumes using fluorine NMR.
    • Obtained porosity distributions that are comparable to those derived from size exclusion chromatography.
    • Demonstrated the applicability of the method to both packed columns and bulk resins.

    Conclusions:

    • The developed fluorine NMR method provides a viable and novel approach for characterizing resin porosities and void volumes.
    • This technique offers an alternative to chromatographic methods, notably by not requiring packed columns.
    • The method is effective for determining pore size distributions in various resinous materials.