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Updated: Aug 12, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
Published on: July 8, 2021
Biological evaluation of biomaterials for cardiovascular applications: some current results
Abstract:
The proper biologic evaluation of biomaterials for blood-contacting applications must include considerations of hemorheologic parameters, species-related differences, and damages to the reticuloendothelial system. Although there are no materials currently available that are completely blood compatible, several smooth-surfaced polymers are quite tolerable in the physiological environment. These include chemically grafted polyacrylamide hydrogels, glow-discharge polymers of silica-free hexamethldisiloxane, and ethyl cellulose perfluorobutyrate.
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