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Curing children with leukemia in West Virginia
A K Ritchey1, K A Starling, F G Keller
1West Virginia University School of Medicine, Morgantown, USA.
The West Virginia Medical Journal
|July 1, 1997
Summary
Childhood leukemia outcomes in West Virginia are promising. Most children with B-lineage acute lymphoblastic leukemia (ALL) treated by pediatric oncology teams achieved long-term remission, indicating high curability.
Area of Science:
- Pediatric Oncology
- Hematology
- Cancer Research
Background:
- Leukemia is the most common childhood cancer, with acute lymphoblastic leukemia (ALL) being the most frequent subtype.
- Historically fatal, leukemia is now highly curable with modern treatments.
- Understanding regional treatment outcomes is crucial for improving pediatric cancer care.
Purpose of the Study:
- To evaluate the treatment outcomes for children and adolescents diagnosed with B-lineage ALL in West Virginia.
- To compare these outcomes with national data for childhood leukemia.
Main Methods:
- A retrospective analysis was conducted on patients diagnosed with B-lineage ALL between February 1986 and January 1991.
- Patients were treated by pediatric oncology teams in Morgantown and Charleston, West Virginia, adhering to a uniform treatment protocol.
Main Results:
- Out of 41 identified patients, 29 (71%) achieved disease-free survival for over two years post-therapy, considered cured.
- Five of the 10 patients who relapsed are now disease-free after rescue therapy, indicating potential cures.
- An overall survival rate of 85% was observed, with 35 out of 41 children alive and disease-free.
Conclusions:
- Treatment outcomes for childhood ALL in West Virginia are comparable to national averages.
- Pediatric oncology team-based treatment in West Virginia offers a high probability of cure for children with ALL.
- This study highlights the effectiveness of standardized treatment protocols in achieving favorable outcomes for pediatric leukemia.
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