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[Bone metabolic disease associated with celiac disease]
1Sección de Intestino Delgado, Hospital Municipal de Gastroenterología Dr. Carlos Bonorino Udaondo, Universidad del Salvador, Catedra de Gastroenterología, Buenos Aires, Argentina.
Gastroenterologia Y Hepatologia
|April 1, 1997
Summary
Celiac disease frequently causes bone loss (osteopenia and osteoporosis) due to accelerated bone breakdown. A gluten-free diet is crucial for bone remineralization in these patients.
Area of Science:
- Endocrinology
- Gastroenterology
- Orthopedics
Context:
- Celiac disease is associated with a high prevalence of osteopenia and osteoporosis.
- Skeletal integrity is compromised in patients with celiac disease.
Purpose:
- To investigate the pathogenesis of bone disease in celiac disease.
- To highlight diagnostic methods and treatment efficacy for skeletal complications.
Summary:
- Celiac disease pathogenesis involves accelerated bone catabolism and negative calcium balance, leading to secondary hyperparathyroidism.
- Diagnosis necessitates bone mineral density assessment in all adult celiac patients.
- A gluten-free diet promotes significant bone remineralization.
Impact:
- Understanding the mechanisms of bone loss in celiac disease.
- Emphasizing the importance of bone density screening.
- Demonstrating the therapeutic benefit of dietary intervention for skeletal health in celiac disease.