Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acute rheumatic fever. Still a challenge

N A da Silva1, B A Pereira

  • 1Department of Pediatrics, Faculdade de Medicina, Universidade Federal de Goiás, Goitânia-Goiás, Brazil.

Rheumatic Diseases Clinics of North America
|August 1, 1997
PubMed
Summary

Acute rheumatic fever (ARF), a challenge worldwide, stems from Streptococcus infection with unclear pathogenesis. Future strategies require public health measures and vaccines to combat this disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biophysical Properties of Three Light-cured Pulp Capping Materials.

Operative dentistry·2025
Same author

Chlorogenic acid improves the quality of boar semen subjected to cooled storage at 15°C.

Andrologia·2018
Same author

Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI.

European journal of nuclear medicine and molecular imaging·2018
Same author

Mestizos with systemic lupus erythematosus develop renal disease early while antimalarials retard its appearance: data from a Latin American cohort.

Lupus·2013
Same author

Effect of the addition of IGF-I and vitamin E to stored boar semen.

Animal : an international journal of animal bioscience·2012
Same author

Addition of IGF-I to storage-cooled boar semen and its effect on sperm quality.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society·2011

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Background:

  • Acute rheumatic fever (ARF) presents a significant global health challenge, despite a prior decline.
  • The condition arises from upper airway infections by group A beta-hemolytic Streptococcus, though precise pathogenic mechanisms remain elusive.
  • While the immune system's role is increasingly understood, genetic host factors in ARF pathogenesis require further investigation.

Purpose of the Study:

  • To summarize the current understanding of acute rheumatic fever (ARF) challenges.
  • To highlight diagnostic complexities and treatment limitations.
  • To propose future directions for ARF control.

Main Methods:

  • Review of existing literature on ARF epidemiology, pathogenesis, diagnosis, and treatment.
  • Analysis of the impact of penicillin on ARF incidence and recurrence.
  • Evaluation of current prophylaxis strategies and their limitations.

Main Results:

  • ARF diagnosis relies on clinical criteria and is prone to over- and underdiagnosis.
  • Penicillin is effective in reducing ARF incidence and recurrence.
  • Current prophylaxis regimens face challenges and frequent failures.

Conclusions:

  • Effective control of ARF necessitates improved public health initiatives.
  • Development and implementation of vaccine strategies are crucial for future ARF prevention.
  • Addressing diagnostic and therapeutic challenges is essential to reduce the global burden of ARF.

Related Experiment Videos