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Bile reflux in columnar-lined esophagus
1Department of Gastroenterology, Cleveland Clinic Foundation, Ohio, USA.
Gastroenterology Clinics of North America
|October 6, 1997
Abstract:
Barrett's esophagus represents a metaplastic process in which the normal squamous epithelium of the lower esophagus is replaced by metaplastic columnar epithelium. Although the role of acid and pepsin in the development of Barrett's esophagus is well accepted, the importance of duodenogastroesophageal reflux in this disorder is not clear.