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[Autoregulation in ischemia of the optic nerve in the human]
1Institut de Recherches en Ophtalmologie, Sion.
Klinische Monatsblatter Fur Augenheilkunde
|May 1, 1997
Abstract
Background:
Autoregulation is defined as the maintenance of constant blood flow in a vascular system in spite of changes in perfusion pressure (PPm).
Materials And Methods:
PPm was decreased by increasing the intraocular pressure (IOP) with a suction cup and optic nerve blood flow was measured with the laser Doppler flowmetry technique (LDF) in 9 normal volunteers.
Results:
The blood flow was autoregulated down to a PPm of 13 mm Hg (IOP = 47 mm Hg).
Conclusions:
These results confirm previous studies in cats and monkeys. The mechanism of autoregulation is probably a decrease in resistance due to capillary recruitment.