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Computed tomographic colonography (Virtual colonoscopy): a new method for detecting colorectal neoplasms
C D Johnson1, A K Hara, J E Reed
1Dept. of Diagnostic Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Endoscopy
|August 1, 1997
Summary
Computed tomographic (CT) colonography offers a new way to view the colon using 2D and 3D images. This technique shows promise for detecting colorectal polyps, with ongoing improvements expected.
Area of Science:
- Radiology
- Gastroenterology
- Medical Imaging
Background:
- Computed tomographic (CT) colonography is an emerging imaging technique.
- It utilizes volumetric CT data and advanced software for colon visualization.
Purpose of the Study:
- To evaluate the performance of CT colonography in detecting colorectal polyps.
- To explore the potential of this technique for colorectal cancer screening.
Main Methods:
- Volumetric CT data acquisition with specific parameters (5 mm slice thickness, 3 mm reconstruction interval, 1.3 pitch, 70 mA).
- Creation of both 2D and 3D images, simulating endoluminal views.
- A blinded, prospective study involving 70 patients.
Main Results:
- Sensitivity for detecting polyps 1 cm or larger was 75%.
- Specificity for polyp detection was 90%.
- Common challenges included retained fluid/stool and suboptimal distension, addressable with supine/prone imaging.
Conclusions:
- CT colonography demonstrates robust performance in detecting colorectal polyps.
- The technique is expected to improve and usher in a new era of colorectal screening.
- Combined 2D and 3D imaging offers the most effective polyp detection.