Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Human bone marrow interferon]

V D Solov'ev, T G Orlova, L M Mentkevich

    Voprosy Virusologii
    |March 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Lipophilic Prodrug of Methotrexate in the Membrane of Liposomes Promotes Their Uptake by Human Blood Phagocytes.

    Acta naturae·2020
    Same author

    IFN-α, IFN-β, and IFN-γ Have Different Effect on the Production of Proinflammatory Factors Deposited in Weibel-Palade Bodies of Endothelial Cells Infected with Herpes Simplex Virus Type 1.

    Bulletin of experimental biology and medicine·2016
    Same author

    O20. Body liquids sectors of puerperal women with preeclampsia and their diagnostic role.

    Pregnancy hypertension·2015
    Same author

    P47. The application of the electrolyte balanced hydroxyethylstarch solution - Tetraspan in complex infusion therapy of preeclampsia in perioperative care.

    Pregnancy hypertension·2015
    Same author

    [The phosphorylation state of transducin beta-subunits].

    Biofizika·2015
    Same author

    [Activation of bovine retinal rod outer segment cGMP-specific phosphodiesterase by the transducin-GTP complex in a physiologically significant range of free calcium ion concentrations].

    Biofizika·2015

    Bone marrow cells can produce interferon, a key antiviral protein, with properties similar to reference preparations. These cells show potential for producing human interferon, matching or exceeding leukocyte interferon

    Area of Science:

    • Immunology
    • Virology
    • Cell Biology

    Context:

    • Interferon production is crucial for antiviral defense.
    • Bone marrow as a potential source for therapeutic agents is under investigation.
    • Previous research focused on other cell types for interferon production.

    Purpose:

    • To investigate the potential of bone marrow cells for interferon production.
    • To characterize the properties and antiviral activity of bone marrow-derived interferon.
    • To evaluate bone marrow cells as a viable source for human interferon preparation.

    Summary:

    • Bone marrow cells from deceased individuals can generate interferon upon stimulation.
    • The interferon produced exhibits comparable properties to established reference preparations.

    Related Experiment Videos

  • Bone marrow interferon demonstrates antiviral activity equal to or greater than leukocyte interferon.

    • Impact:

    • Suggests bone marrow cells as a novel and efficient source for human interferon production.
    • Highlights a potential new avenue for antiviral therapy development.
    • May lead to improved methods for large-scale interferon manufacturing.