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[Diastolic function in patients with coronary artery disease before and after CABG]

Y Kadoi1, F Kawahara, N Fujita

  • 1Saitama Prefectural Ohara-Cardiovascular Center, Saitama.

Masui. the Japanese Journal of Anesthesiology
|November 22, 1997
PubMed

Insights

Coronary artery disease patients showed improved diastolic function after angioplasty. Transesophageal echocardiography revealed partial recovery in left ventricular diastolic function one hour post-procedure, particularly in patients with impaired initial function.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Physiology

Background:

  • Coronary artery disease (CAD) significantly impacts cardiac function.
  • Diastolic dysfunction is a key complication of CAD.
  • Assessing diastolic function is crucial for managing CAD patients.

Purpose of the Study:

  • To evaluate changes in diastolic cardiac function post-coronary angioplasty.
  • To compare diastolic function parameters before and after the intervention.
  • To identify patient subgroups benefiting most from angioplasty regarding diastolic function.

Main Methods:

  • Transesophageal echocardiography (TEE) was used in 16 CAD patients.
  • Pulsed Doppler measured peak early (E) and late (A) diastolic filling velocities and their velocity time integrals (VTI-E, VTI-A).
  • Patients were stratified into Group A (E/A ≥ 1) and Group B (E/A < 1).

Main Results:

  • Significant differences observed between groups in E-acceleration time and VTI 0-33%/total VTI pre-angioplasty (P < 0.05).
  • Group B demonstrated significant changes in E-deceleration time and slope post-angioplasty (p < 0.05).
  • Partial recovery of left ventricular diastolic function was noted in Group B one hour after coronary angioplasty.

Conclusions:

  • Coronary angioplasty can lead to improvements in diastolic cardiac function.
  • Patients with initially impaired diastolic function (Group B) show measurable recovery post-intervention.
  • TEE is effective in assessing these functional changes in CAD patients.

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