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Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
Published on: April 13, 2015
[Diastolic function in patients with coronary artery disease before and after CABG]
Y Kadoi1, F Kawahara, N Fujita
1Saitama Prefectural Ohara-Cardiovascular Center, Saitama.
Abstract:
We evaluated diastolic cardiac function in 16 patients with coronary artery disease before and after coronary angioplasty using transesophageal echocardiography. Peak early diastolic and late diastolic filling velocities (E wave and A wave) and velocity time integrals of early and late diastolic filling (VTI-E and VTI-A) were measured by pulsed doppler echocardiography. The patients were divided into two groups: Group A; E/A > or = 1. Group B; E/A < 1. There were statistical differences between the two groups in E-acceleration time and VTI 0-33%/ total VTI at pre-coronary angioplasty period (P < 0.05). There were statistical differences in E-decelaration time and E-decelaration slope of group B before and after coronary angioplasty (p < 0.05). These results suggest that the left ventricular diastolic function in group B has recovered partly at one hour after coronary angioplasty.
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