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[The neurobiological bases of epileptogenesis in the developing brain]
Uspekhi Fiziologicheskikh Nauk
|July 1, 1997
Abstract:
The basics of neurophysiological, neurochemical and molecular mechanisms of epileptogenesis in early ontogeny are discussed. The role of developmental neuropathology, synaptogenesis; the role of glutamatergic and GABA-ergic transmitter systems are summarized. The candidates of genes in the childhood epilepsies, developmental changes in the expression of genes of voltage-gated ionic channels and receptor genes are reviewed.