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Updated: Aug 6, 2026

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
Published on: May 21, 2010
[The cerebellar cortical atrophy syndrome]
Abstract:
The results of the observation of 44 patients with cerebellar syndrome of different etiology are presented. Together with careful study of anamnestic and clinical data some additional examinations were performed: senso- and pallesthesiometry, thermovisional investigation, vestibulometry, electroencephalo-, electromyography, computer tomography. The study allowed to reveal both the cause of the disease and to refer etiologically late cerebellar cortical ataxia to alcohol factor. On the basis of the comparison of clinical neurological data with paraclinical observation differential diagnostic criteria were defined for Marie-Foix-Alajouanine's late cortical cerebellar atrophy in alcoholism, in the cases of the hereditary predisposition as well as of unclear genesis, in Holmes olivocerebellar atrophy, in Menzel, Hunt and Déjérine-Thomas olivopontocerebellar degeneration.
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