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Magnetization transfer imaging of bone marrow with and without fat suppression
1Department of Radiology, Nippon Medical School, Tokyo, Japan.
Rationale And Objectives:
To assess magnetization transfer (MT) ratios of bone marrow at magnetic resonance (MR) imaging performed with and without fat suppression.
Materials And Methods:
The authors performed MR imaging in 30 regions of normal bone marrow in 10 subjects by using four types of gradient-echo sequences: a combination of MT and fat-suppression techniques, only the fat-suppression technique, only the MT technique, and without MT or fat-suppression techniques. MT ratios of marrow obtained with and without the fat-suppression technique were quantitatively compared.
Results:
The average MT ratio of marrow with fat suppression was significantly higher than that without fat suppression (P < .01).
Conclusion:
Because bone marrow includes both water and fat, the MT ratio of marrow was underestimated when MT imaging was performed without fat suppression. A fat-suppression technique should be used.