Synthesis and antifungal activity of some new arylidenamino compounds

A series of 3-alkyl/aryl-4-arylidenamimo-4,5-dihydro-1H-1,2,4- triazol-5-ones was synthesized and characterized by elemental and spectral analysis. These compound were tested for in vitro antibacterial and antifungal activity in solid agar cultures against eight microorganisms. In these test, some of the new compounds were shown to be very potent in vitro antifungal activity against the used fungi.