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The effects of methylmethacrylate's hyperthermic polymerization on cerebral vascular permeability
D F Jimenez1, C M Barone, T Tigno
1Division of Neurosurgery, University of Missouri Health Sciences Center, Columbia, USA.
Acta Neurochirurgica. Supplement
|January 1, 1997
Abstract:
This study was undertaken to analyze the effects of significant hyperthermia (> 100 degrees C) associated with the polymerization of polymethlymethacrylate (PMM) on the permeability of the cerebral vasculature in rats. The method used to visualize the pial vasculature included the open pial window technique and epifluorescence microscopy. Results indicated that there is a significant increase in cerebral vascular permeability following in situ polymerization of PMM over the craniectomy site.