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Tissue ablation with radiofrequency using multiprobe arrays

S N Goldberg1, G S Gazelle, S L Dawson

  • 1Department of Radiology, Massachusetts General Hospital, Boston 02114, USA.

Academic Radiology
|August 1, 1995
PubMed
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Multiprobe radiofrequency arrays can increase tissue destruction volume. Optimal results for radiofrequency tissue coagulation are achieved with closely spaced probes (≤1.5 cm) applied simultaneously.

Area of Science:

  • Medical Devices
  • Surgical Technology
  • Radiofrequency Ablation

Background:

  • Radiofrequency (RF) tissue coagulation is a key technique in minimally invasive surgery.
  • Current methods using single probes may limit the volume of tissue ablated per session.
  • Optimizing multiprobe array configurations is crucial for enhancing ablation efficiency.

Purpose of the Study:

  • To assess the feasibility of increasing tissue volume destroyed by RF tissue coagulation using multiprobe arrays.
  • To define parameters influencing lesion size and shape in multiprobe RF ablation.
  • To compare simultaneous versus sequential RF application in multiprobe arrays.

Main Methods:

  • Ex vivo calf liver tissue was treated with 2-5, 18-gauge RF probes.

Related Experiment Videos

  • Probe spacing (1-3 cm) and arrangement were varied.
  • RF energy was applied simultaneously or sequentially at 70-90°C for 6 minutes.

    • Main Results:

    • Simultaneous RF application with probes ≤1.5 cm apart resulted in uniform tissue necrosis.
    • Three equidistant probes (1.5 cm spacing) created spheroid lesions (~3.0 cm diameter).
    • Four equidistant probes (1.5 cm spacing) created cuboid lesions (~3.2 cm sides).
    • Probes ≥2 cm apart produced independent lesions with incomplete necrosis between them.
    • Simultaneous application yielded greater necrosis than sequential application.

    Conclusions:

    • Multiprobe RF arrays can ablate larger tissue volumes in a single session compared to individual probes.
    • Probes spaced ≤1.5 cm apart exhibit synergistic effects, increasing coagulated tissue volume.
    • Simultaneous application of RF energy with closely spaced probes is more effective for maximizing ablation volume.