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[The effectiveness of polymethylsiloxane as a hemosorbent in experiments on obstructive jaundice]

V L Popov1, I V Sobko, I M Samodumova

  • 1Ukrainskiĭ gosudarstvennyĭ konsortsium "Ekosorb", Voenno-meditsinskiĭ institut Ukrainskoĭ voenno-meditsinskoĭ akademii, Nauchno-promyshlennyĭ tsentr "Sorbtsia", g. Kiev.

Klinichna Khirurhiia
|January 1, 1997
PubMed

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Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...