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Ceramic drug-delivery devices

A Lasserre1, P K Bajpai

  • 1Department of Biology, University of Dayton, OH 45469, USA.

Critical Reviews in Therapeutic Drug Carrier Systems
|April 2, 1998
PubMed
Summary
This summary is machine-generated.

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Ceramics offer versatile drug delivery systems for various therapeutic agents. This review explores their advantages and disadvantages compared to conventional methods.

Area of Science:

  • Biomaterials Science
  • Materials Science
  • Drug Delivery

Background:

  • Ceramics are utilized in various drug delivery systems for controlled release of chemicals, biologicals, and drugs.
  • These systems are implanted at different sites for desired therapeutic durations.
  • Both in vitro and in vivo studies confirm the efficacy of ceramics in drug delivery applications.

Purpose of the Study:

  • To review the advantages and disadvantages of conventional drug delivery systems.
  • To explore different ceramic-based approaches for delivering chemical and biological agents.
  • To provide a comprehensive overview of ceramic drug delivery technologies.

Main Methods:

  • Literature review of ceramic drug delivery systems.
  • Analysis of in vitro and in vivo study findings.

Related Experiment Videos

  • Comparison of ceramic systems with conventional drug delivery methods.
  • Main Results:

    • Ceramics can be fabricated into various forms like matrices, inserts, reservoirs, cements, and particles.
    • A wide range of therapeutic agents, including antibiotics, anticancer drugs, hormones, and vaccines, can be delivered using ceramic systems.
    • Ceramic drug delivery offers controlled release profiles for extended periods.

    Conclusions:

    • Ceramic-based drug delivery systems present a viable alternative to conventional methods.
    • Further research into ceramic properties can optimize drug release kinetics and therapeutic outcomes.
    • The versatility of ceramics makes them promising for future advancements in targeted and sustained drug delivery.