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Clinical experience with cyanoacrylate tissue adhesive
M Moschos1, D Droutsas, P Boussalis
1Department of Ophthalmology, University of Athens, Greece.
Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1996
Summary
Cyanoacrylate tissue adhesive is a safe and effective method for healing corneal perforations, even in severe cases. This technique successfully avoided enucleation in 385 patients, with minimal complications like ocular hypotony and infection.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- Corneal perforations pose significant risks, often necessitating complex surgical interventions.
- Traditional treatments for corneal wounds can be associated with considerable complications.
Purpose of the Study:
- To investigate the indications, outcomes, and complications of using cyanoacrylate tissue adhesive in managing corneal perforations.
- To evaluate the efficacy of cyanoacrylate adhesive as a conservative treatment for corneal wounds.
Main Methods:
- A retrospective study of 385 cases treated with cyanoacrylate tissue adhesive between 1980 and 1995.
- In cases of large perforations (>3 mm), a nylon suture reticulum was created before adhesive application.
- Early application of bandage contact lenses and topical antibiotics was employed post-procedure.
Main Results:
- Only three cases of ocular hypotony and two of microbial infection were reported among 385 patients.
- Enucleation was avoided even in severe cases involving large corneal perforations and ocular infection.
- The combined approach of adhesive, bandage contact lens, and antibiotics resulted in a low infection incidence.
Conclusions:
- Cyanoacrylate tissue adhesive provides a safe and effective technique for healing corneal wounds.
- This method offers a viable alternative to tectonic penetrating keratoplasty, reducing associated risks.
- The study demonstrates encouraging outcomes for managing corneal perforations with cyanoacrylate adhesive.