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Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Updated: Jul 26, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Pediatric wound infections: a prospective multicenter study

J R Horwitz1, W J Chwals, J J Doski

  • 1University of Texas-Houston Medical School and Hermann Children's Hospital, USA.

Annals of Surgery
|May 1, 1998
PubMed
Summary

Pediatric surgical wound infections occur in 4.4% of cases. Factors like contamination and operation duration, not patient health status, significantly increase infection risk in children.

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Area of Science:

  • Pediatric Surgery
  • Infectious Disease Epidemiology

Background:

  • Surgical wound infections (SWI) are a major cause of postoperative morbidity in children.
  • Limited North American data exists on pediatric SWI incidence and risk factors.

Purpose of the Study:

  • To prospectively determine the incidence of SWI in children across multiple institutions.
  • To identify risk factors associated with SWI development in pediatric surgical patients.

Main Methods:

  • Prospective follow-up of infants and children for 30 days post-operation.
  • Data collected from pediatric surgical services at three institutions over 17 months.

Main Results:

  • Overall SWI incidence was 4.4% in 846 patients.
  • Significant risk factors for SWI included intraoperative contamination (p=0.006) and operation duration (p=0.03).
  • No significant differences in SWI rates were found based on patient age, sex, ASA score, or preoperative status.

Conclusions:

  • Pediatric SWI are primarily linked to intraoperative factors rather than patient's overall physiological condition.
  • Performing procedures in the intensive care unit does not increase SWI incidence.