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Updated: Aug 18, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Uterine and ovarian conservation in advanced small cell carcinoma of the ovary
J L Powell1, R D McAfee, R C McCoy
1Department of Obstetrics and Gynecology, Coastal Area Health Education Center, New Hanover Regional Medical Center, Wilmington, North Carolina 28402-9025, USA.
Background:
The decision to recommend removal or conservation of a normal ovary and uterus in a young woman with advanced ovarian cancer is difficult and controversial.
Case:
A 21-year-old patient with a large-cell variant of small-cell carcinoma of the ovary stage IIIc underwent optimal debulking surgery with preservation of the normal appearing uterus and opposite adnexa followed by aggressive multi-agent chemotherapy. She is menstruating normally and is free of disease, more than 2 years since completion of chemotherapy.
Conclusion:
In selected cases, conservation of the uninvolved ovary and uterus in patients with advanced-stage, small-cell carcinoma of the ovary may not compromise survival.

