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Updated: Aug 10, 2026

Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
Published on: February 11, 2019
Esophagolaryngeal reflex in a porcine animal model
1Department of Surgery, University of British Columbia, Vancouver.
Objective:
The purpose of this study was to determine the effect of stimulation of the distal esophagus upon tension in the thyroarytenoid muscles.
Method:
Stimulation of the distal esophagus of six anaesthetized female pigs by means of balloon dilatation and acid infusion was performed. Response was measured with electromyography of the thyroarytenoid muscles.
Results:
Acid infusion into the distal esophagus showed a statistically significant response in the thyroaytenoid muscles. Response to balloon dilatation was marked but not statistically significant.
Conclusion:
Stimulation of the distal esophagus during episodes of gastroesophageal reflux may play a causative role in producing some of the symptoms that otolaryngologists treat on a daily basis.
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