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Synthesis and antitumor activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones
A A Ikizler1, A Ikizler, M Serdar
1Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
Acta Poloniae Pharmaceutica
|May 19, 1998
Abstract:
Eight new 3-alkyl(aryl)-4-arylidenamino-4,5-dihydro-1H-1,2,4-triazol-5 - ones were synthesized and characterised by elemental analysis. 1H NMR, IR and UV spectra. Seven new and 34 recently reported derivatives of 4,5-dihydro-1H-1,2,4 triazol-5-one ring were screened for their antitumor activities.