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Synthesis and properties of carbocyclic oligothymidylate lacking the 5'-methylene
1Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama, Japan.
Nucleic Acids Symposium Series
|January 1, 1997
Abstract:
Oligodeoxynucleotides possessing a shortened internucleotidic linkage have been prepared using carbocyclic nucleosides lacking the 5'-methylene as the monomeric units. Specifically, the oligomers derived from carbocyclic 5'-n or thymidine and 2'-hydroxy-3'-deoxythymidine will be described.