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[Functioning and non-functioning parathyroid cysts: entities with different origin and clinical characteristics in 2
L Mosso1, J M López, P Trincado
1Departamento de Endocrinología, Pontificia Universidad Católica de Chile.
Revista Medica De Chile
|May 22, 1998
Summary
This study details two cases of parathyroid cysts in young women. Diagnosis was confirmed through imaging and high parathyroid hormone (PTH) levels, leading to surgical removal.
Area of Science:
- Endocrinology
- Surgical Pathology
- Diagnostic Imaging
Background:
- Parathyroid cysts are rare benign lesions.
- They can present as neck masses or with hormonal abnormalities.
- Distinguishing them from other thyroid or parathyroid conditions is crucial.
Observation:
- Two female patients, aged 20 and 11, presented with cystic lesions in the thyroid lobe.
- The 20-year-old exhibited hypercalcemia and elevated parathyroid hormone (PTH) levels.
- Ultrasound and CT scans identified cystic nodules; needle aspiration in one case revealed high PTH concentration.
Findings:
- Surgical excision and subsequent pathological examination confirmed parathyroid cysts in both patients.
- The cyst fluid in the symptomatic patient contained significantly elevated PTH levels.
- The asymptomatic patient's cyst was also pathologically confirmed as parathyroidal.
Implications:
- Parathyroid cysts should be considered in the differential diagnosis of cystic neck masses, especially with concurrent hypercalcemia.
- Diagnostic evaluation including PTH level measurement is essential for accurate diagnosis.
- Surgical management is curative for symptomatic or pathologically confirmed parathyroid cysts.