Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Melanoma complicating pregnancy

R C Squatrito1, S P Harlow

  • 1Division of Gynecologic Oncology, University of Vermont, Burlington, USA.

Obstetrics and Gynecology Clinics of North America
|June 18, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sentinel lymph node biopsy in breast cancer.

Breast disease·2005
Same author

Sentinel lymph node--why study it: implications of the B-32 study.

Seminars in surgical oncology·2001
Same author

Gamma probe guided biopsy of the sentinel node in malignant melanoma: a multicentre study.

Melanoma research·2001
Same author

Cyclosporin A reverses chemoresistance in patients with gynecologic malignancies.

Neoplasia (New York, N.Y.)·2000
Same author

Pathologic analysis of sentinel and nonsentinel lymph nodes in breast carcinoma: a multicenter study.

Cancer·2000
Same author

Intraoperative ultrasound localization to guide surgical excision of nonpalpable breast carcinoma.

Journal of the American College of Surgeons·1999

Malignant melanoma in pregnancy is increasing. Early detection and prompt surgical treatment are key, as pregnancy does not appear to worsen prognosis when other factors are controlled.

Area of Science:

  • Oncology
  • Dermatology
  • Obstetrics

Background:

  • Malignant melanoma incidence is rising globally.
  • Melanoma may be the most common malignancy diagnosed during pregnancy.
  • Effective treatments for advanced or metastatic melanoma are limited.

Purpose of the Study:

  • To review the current literature on malignant melanoma in pregnancy.
  • To assess the impact of pregnancy on melanoma prognosis.
  • To provide guidance on the management of melanoma during pregnancy.

Main Methods:

  • Comprehensive literature review of prominent reports on melanoma in pregnancy.
  • Analysis of prognostic variables and their impact on outcomes.
  • Evaluation of treatment strategies, including surgery, chemotherapy, and biologic therapy.

Related Experiment Videos

Main Results:

  • No consensus exists on whether pregnancy worsens melanoma prognosis.
  • After controlling for prognostic variables, outcomes appear unchanged.
  • Patients diagnosed during pregnancy may present with higher-risk lesions and increased tumor thickness.
  • Prompt surgical intervention is recommended, avoiding general anesthesia in the first trimester.

Conclusions:

  • Pregnancy itself does not appear to negatively impact melanoma prognosis when adjusted for known factors.
  • Vigilant surveillance for early detection and prompt treatment are crucial for pregnant individuals.
  • Adjuvant chemotherapy or biologic therapy during pregnancy is not yet supported by sufficient evidence.