[Multicenter study of intracoronary stent implantation in Rio de Janeiro]

Prior research has shown that intracoronary stent implantation is a widely used procedure for treating coronary artery disease. However, the long-term safety and efficacy of stent implantation in diverse clinical settings remain unclear. Established knowledge includes the use of various stent types and the importance of procedural success rates. No prior work had resolved the specific outcomes of stent implantation in a multicenter setting in Rio de Janeiro. This gap motivated the need for a retrospective analysis across multiple hospitals to assess real-world application. The study aimed to address uncertainties about stent types, procedural techniques, and post-implantation outcomes. No prior work had resolved the specific complications and success rates in this geographic and clinical context. The absence of standardized data on late outcomes in this region prompted the investigation. The study sought to clarify the safety profile and effectiveness of stent implantation in a real-world setting.

The purpose of this study was to evaluate the outcomes of intracoronary stent implantation in patients with coronary artery disease across seven hospitals in Rio de Janeiro. The researchers aimed to assess both early and late procedural outcomes, including success rates and complication frequencies. They sought to determine the safety and effectiveness of stent implantation in a real-world clinical setting. The study focused on a retrospective analysis of 783 procedures performed between June 1994 and December 1996. The motivation stemmed from the need to understand stent implantation outcomes in a multicenter environment. No prior work had resolved the specific outcomes of stent implantation in this geographic and clinical context. The study aimed to provide insights into the use of various stent types and procedural techniques. The goal was to contribute to the understanding of stent implantation safety and efficacy in a diverse patient population.

The study employed a retrospective design, analyzing data from 783 stent implantation procedures conducted in 660 patients across seven hospitals in Rio de Janeiro. Coronary angiography was used to assess outcomes without digital subtraction. A variety of stent types were utilized, including Palmaz-Schatz, Gianturco-Roubin, and NIR models. Procedures were performed using high-pressure balloon inflation without intracoronary ultrasound guidance. The study categorized stent implantation indications into five groups, including de novo lesions and restenotic lesions. Sub-acute stent thrombosis prevention was managed with ticlopidine and aspirin in most cases. Early and late outcomes were evaluated using clinical follow-up and coronary angiography data. The study aimed to capture both procedural success and long-term event rates.

The early success rate of stent implantation was 98.0% in 770 lesions across 646 patients. Clinical success was achieved in 96.0% of 634 patients. Major complications included acute myocardial infarction in 1.1% of cases. Coronary artery bypass grafting was required in 1.4% of patients. Vascular complications with surgical correction or bleeding occurred in 3.0% of cases. Late follow-up showed in-stent lesions in 19.8% of 121 patients who underwent coronary angiography. Myocardial infarction occurred in 1.5% of patients during late follow-up. Coronary bypass was needed in 2.3% of cases, and death occurred in 1.0% of patients.

The authors reported that stent implantation for coronary artery disease can be performed safely with a high early success rate. Few complications were observed during the early post-procedural period. The late follow-up showed a low rate of cardiac events, including myocardial infarction and death. The study suggests that stent implantation is a viable option for treating coronary artery disease in a multicenter setting. The use of various stent types did not significantly affect outcomes. The findings indicate that stent implantation can be effective in a diverse patient population. The authors propose that the procedure is associated with few complications and a favorable long-term safety profile. The results suggest that stent implantation is a suitable intervention for managing coronary artery disease in real-world clinical settings.