Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Models for 1/f noise in nerve membranes

M B Weissman

    Biophysical Journal
    |September 1, 1976
    PubMed
    Summary

    A proposed model for nerve membrane 1/f noise is mathematically inconsistent. A new, self-consistent model is introduced, focusing on lipid orientation fluctuations for improved accuracy in nerve membrane noise analysis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Do GRE scores help predict getting a physics Ph.D.? A comment on a paper by Miller <i>et al.</i>

    Science advances·2020
    Same author

    Anomalous noise in the pseudogap regime of YBa2Cu3O(7-delta).

    Physical review letters·2010
    Same author

    Electronic transport in underdoped YBa2Cu3O7-delta nanowires: evidence for fluctuating domain structures.

    Physical review letters·2004
    Same author

    Artificial dielectric superlattices with broken inversion symmetry.

    Physical review letters·2003
    Same author

    Barkhausen noise in a relaxor ferroelectric.

    Physical review letters·2002
    Same author

    Density-noise power fluctuations in vibrated granular media.

    Physical review. E, Statistical, nonlinear, and soft matter physics·2001

    Area of Science:

    • Biophysics
    • Neuroscience
    • Physical Chemistry

    Background:

    • Previous models for 1/f noise in nerve membranes, such as the one by Clay and Schlesinger (1976) and Lundström and McQueen (1974), have been proposed.
    • These models are crucial for understanding the electrical properties and signaling mechanisms of nerve cells.
    • However, existing models may contain mathematical inconsistencies that limit their predictive power and biological relevance.

    Purpose of the Study:

    • To identify and analyze the mathematical inconsistencies within a recently proposed model for 1/f noise in nerve membranes.
    • To develop and present a new, self-consistent theoretical model for nerve membrane noise.
    • To explain nerve membrane noise phenomena by incorporating lipid orientation fluctuation effects.

    Main Methods:

    • Mathematical analysis of the existing 1/f noise model to pinpoint inconsistencies.
    • Development of a theoretical framework for a new model based on biophysical principles.
    • Incorporation of membrane lipid dynamics and orientation fluctuations into the new model.

    Main Results:

    • The previously proposed model for nerve membrane 1/f noise was found to possess significant mathematical inconsistencies.
    • A novel, self-consistent model was successfully formulated.
    • The new model effectively accounts for noise generation through lipid orientation fluctuations in the nerve membrane.

    Conclusions:

    • The existing 1/f noise model for nerve membranes is mathematically flawed.
    • A revised, self-consistent model provides a more accurate theoretical basis for understanding nerve membrane noise.
    • Lipid orientation fluctuations are a key factor in generating 1/f noise in nerve membranes.

    Related Experiment Videos