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A vibrating trachea

M J Doherty1, D P Spence, D Graham

  • 1Aintree Chest Centre, Fazakerley Hospital, Liverpool, UK.

Thorax
|July 11, 1998
PubMed
Summary
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Relapsing polychondritis can cause tracheomalacia, leading to a unique expiratory sound. This sound, caused by airflow-induced flutter in the trachea, supports the dynamic flutter theory of wheeze production.

Area of Science:

  • Pulmonology
  • Internal Medicine
  • Pathology

Background:

  • Relapsing polychondritis is a rare systemic autoimmune disease affecting cartilage.
  • Tracheomalacia, or the collapse of the trachea, can be a rare manifestation of relapsing polychondritis.
  • Wheezing is a common respiratory symptom, but its precise acoustic mechanisms are debated.

Observation:

  • A case of relapsing polychondritis presenting with tracheomalacia exhibited an unusual low-pitched expiratory sound.
  • This sound was audible at the mouth and chest wall, correlating with expiratory airflow limitation.
  • Flow trace analysis revealed oscillations of approximately 50 Hz during expiration.

Findings:

  • Spectral analysis of the expiratory sound demonstrated characteristics similar to sounds produced by flutter in flexible tubes.

Related Experiment Videos

  • The findings suggest the sound originated from airflow-induced flutter within the trachea and main airways.
  • This observation provides further evidence for the dynamic flutter theory of wheeze generation.

    • Implications:

    • This case highlights a unique acoustic sign associated with tracheomalacia in relapsing polychondritis.
    • The findings support the dynamic flutter theory as a mechanism for wheeze production in certain airway conditions.
    • Understanding these mechanisms can aid in the diagnosis and management of complex respiratory symptoms in rare diseases.