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Updated: Aug 3, 2026

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Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
Published on: June 20, 2019
Biochemical and biological analyses of farnesyl-protein transferase inhibitors
N E Kohl1, K S Koblan, C A Omer
1Department of Cancer Research, Merck Research Laboratories, West Point, PA, USA.
Methods in Molecular Biology (Clifton, N.J.)
|July 17, 1998
Abstract:
The methods outlined in Subheading 3. provide a logical sequence of assays with which to evaluate the biochemical and biological properties of potential FPTase inhibitors. The clinical predictability of these assays must await the evaluation of one or more of these compounds in humans.

