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Synthesis and biological activities of some 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives
A A Ikizler1, A Demirbas, C B Johansson
1Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
Acta Poloniae Pharmaceutica
|July 22, 1998
Abstract:
Nine new 1,3,4-trisubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterized by elemental analysis, 1H NMR, IR and UV spectra. These new and 30 recently reported 3,4-disubstituted- and 1,3,4-trisubstituted-4,5-dihydro-1H-1,3,4-triazol-5-ones were screened for antibacterial, antitumor and anti-HIV activities.