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[The role of polyol pathways in formation of diabetic cataracts]
K Sabasiński1, J Andrzejewska-Buczko
1Katedry i Kliniki Okulistyki AM w Białymstoku.
Klinika Oczna
|January 1, 1997
Abstract:
The authors present current knowledge concerning the role of polyols in the formation of cataract in diabetic patients. Sugar alcohols are formed in lens as a consequence of glucose conversion in the sorbitol pathway. The pharmacological modulation of this process by the application of aldose reductase inhibitors are also discussed.