Related Experiment Videos
Influence of sperm surface antibodies on spontaneous pregnancy rates
K Abshagen1, H M Behre, T G Cooper
1Institute of Reproductive Medicine, University of Münster, Germany.
Objective:
To determine the rates of spontaneous pregnancies among women whose infertile male partners had sperm surface antibodies.
Design:
Retrospective analysis.
Setting:
Infertility clinic of a university referral center.
Patient(S):
One hundred fifty-seven infertile couples; the male partner had IgA and/or IgG sperm surface antibody concentrations of >10%.
Intervention:
None.
Main Outcome Measure(S):
Spontaneous pregnancy rates (PRs) over 6 years.
Result(S):
Spontaneous PRs correlated negatively with antibody concentrations.
Conclusion(S):
Although the chance of spontaneous pregnancy among women whose partners had sperm antibody concentrations of <50% was good, intracytoplasmic sperm injection should be recommended to patients with concentrations of >90%.