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[Ocular changes in primary hematologic diseases]

G E Lang1, C W Spraul, G K Lang

  • 1Universitäts-Augenklinik Ulm.

Klinische Monatsblatter Fur Augenheilkunde
|August 26, 1998
PubMed
Summary
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Ocular manifestations are common in hematological diseases, affecting up to 90% of patients. These eye changes, often asymptomatic, range from common retinal hemorrhages to rarer optic nerve issues.

Area of Science:

  • Ophthalmology
  • Hematology
  • Oncology

Context:

  • Hematological diseases frequently present with ocular manifestations.
  • Ocular changes occur in up to 90% of patients, varying by underlying condition.
  • Many patients with ocular manifestations remain asymptomatic.

Purpose:

  • To describe the spectrum of ocular manifestations associated with various hematological disorders.
  • To highlight common and rare eye findings in conditions like anemia, leukemia, and lymphomas.
  • To discuss ocular complications arising from treatments such as chemotherapy and bone marrow transplantation.

Summary:

  • Hematological disorders impact all eye structures, with conjunctival pallor, hemorrhages, intraretinal hemorrhages, and cotton wool spots being most frequent.

Related Experiment Videos

  • Less common findings include retinal infiltrates and manifestations affecting the lids, anterior segment, optic nerve, orbit, and adnexa.
  • The review covers ocular signs in anemia, leukemia, lymphomas, myeloproliferative diseases, plasmocytoma, myelodysplastic syndromes, coagulopathies, and reticulo-histiocytic diseases.

    • Impact:

    • Recognizing ocular signs aids in early diagnosis and management of hematological diseases.
    • Understanding these manifestations is crucial for ophthalmologists and hematologists managing patient care.
    • This knowledge helps anticipate and mitigate potential vision-threatening complications from both disease and treatment.