The arterial angioarchitecture in lacunar state

Area of Science:

• Neurology
• Neuroscience
• Cerebrovascular Research

Background:

• Lacunar state is a common finding in the brain.
• Infarcts in the lenticular nuclei and periventricular zones are prevalent.

Purpose of the Study:

• To investigate the relationship between deep arterial angioarchitecture and lacune location.
• To identify occlusions in arteries supplying lacunar infarcts.

Main Methods:

• Statistical analysis of seventy-five brains with lacunar state.
• Translucidation technique on teen brains after arterial system filling with barium sulphate solution.
• Examination of deep perforating arteries for narrowings, dilatations, and occlusions.

Main Results:

• Lenticular nuclei and periventricular zones are the main sites of infarcts.
• Deep perforating arteries showed poor filling, narrowings, and post-stenotic dilatations.
• Occlusion of the responsible artery was found in twenty-four out of thirty lacunes.

Conclusions:

• Deep perforating artery occlusion is a significant factor in lacune formation.
• The location of arterial occlusion correlates with the topography of lacunar infarcts.