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Published on: January 23, 2017
Relationships between otitis media sequelae and age
K A Daly1, L L Hunter, S C Levine
1University of Minnesota Otitis Media Research Center, Department of Otolaryngology, University of Minnesota School of Medicine, Minneapolis 55455, USA.
Insights
Long-term follow-up of children treated for chronic otitis media with effusion (OME) reveals that while OME prevalence decreases with age, significant sequelae like hearing loss and tympanic membrane damage can still develop.
Area of Science:
- Otolaryngology
- Pediatric Audiology
- Medical Research
Background:
- Chronic otitis media with effusion (OME) is common in children.
- Tympanostomy tubes are a frequent treatment for persistent OME.
- Long-term outcomes and age-related sequelae after OME treatment require further investigation.
Purpose of the Study:
- To investigate the relationship between age and the development of sequelae in children treated with tympanostomy tubes for chronic OME.
- To assess long-term outcomes in different age groups following tympanostomy tube insertion.
Main Methods:
- A cross-sectional study design was employed, evaluating sequelae in children, adolescents, and adults.
- Two groups were studied: Group I (prospective follow-up at 4 years post-treatment) and Group II (retrospective evaluation 9-23 years post-treatment).
- Assessments included otomicroscopy, tympanometry, audiometry, and hearing screening.
Main Results:
- Cholesteatoma and perforation rates were low (<1% and <2%, respectively).
- Tympanosclerosis increased with age in Group I (P < .01).
- Older subjects showed higher rates of severe retractions (18% vs. 4%), hearing loss (21% vs. 10%), and severe atrophy (24% vs. 0%), but lower rates of OME (2% vs. 12%) compared to younger subjects.
Conclusions:
- Chronic OME prevalence decreases with age, but significant sequelae can emerge during adolescence and young adulthood.
- Severe tympanic membrane atrophy, retractions, hearing loss, cholesteatoma, and chronic perforations are potential long-term complications.
- Long-term prospective studies are crucial for understanding the progression of sequelae in children with a history of chronic OME.
Objectives:
To explore relationships between age and sequelae in two groups of children treated with tympanostomy tubes for chronic otitis media with effusion (OME).
Study Design:
Cross-sectional study of sequelae among children, adolescents, and adults at 4 years and 9 to 23 years after tympanostomy tube treatment.
Methods:
Group I was examined with otomicroscopy, tympanometry, and audiometry two to four times a year as part of a prospective study, and they were evaluated 4 years after initial tube treatment for this study. Group II received tubes while participating in a chronic OME study, but participants were not followed prospectively after treatment. Nine to 23 years after tube treatment, they were examined with otomicroscopy, tympanometry, and hearing screening.
Results:
Among the 5- to 28- year-old subjects, cholesteatoma (< or = 1%) and perforation (< or = 2%) were rare. In Group I, tympanosclerosis increased with age (P < .01), and OME (flat tympanograms) decreased with age in Group II (P < .01). The older cohort was more likely to have severe retractions (18% vs. 4%, P = .02), hearing loss (21% vs. 10%, P < .01), and severe atrophy (24% vs. 0%, P < .01) than the younger cohort, but they were less likely to have flat tympanograms (2% vs. 12%, P < .01).
Conclusions:
Although OME became less prevalent with age, important sequelae (severe atrophy, severe tympanic membrane retraction, hearing loss, cholesteatoma, and chronic perforation) may develop in children with chronic OME as they become adolescents and young adults. Long-term prospective studies are important in defining the progression of sequelae in these children.
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