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Effect of trabeculectomy on visual field in progressive normal-tension glaucoma
L Daugeliene1, T Yamamoto, Y Kitazawa
1Department of Ophthalmology, Gifu University School of Medicine, Japan.
Japanese Journal of Ophthalmology
|September 28, 1998
Summary
Surgical reduction of intraocular pressure (IOP) can prevent visual field loss in normal-tension glaucoma (NTG). Higher preoperative IOP and no diabetes mellitus were linked to better outcomes in NTG patients.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Surgical Interventions
Background:
- Normal-tension glaucoma (NTG) is characterized by optic nerve damage and visual field loss despite normal intraocular pressure (IOP).
- Understanding factors influencing visual field progression in NTG is crucial for effective management.
- Surgical intervention is a potential treatment to lower IOP and mitigate disease progression.
Purpose of the Study:
- To evaluate the efficacy of surgical treatment in preserving visual field function in normal-tension glaucoma (NTG) eyes.
- To identify clinical factors, both IOP-related and unrelated, associated with visual field progression in NTG patients.
Main Methods:
- Retrospective analysis of 32 patients (32 eyes) with NTG who underwent surgical treatment.
- Stepwise regression analysis was employed to correlate visual field changes with preoperative IOP and other clinical parameters.
Main Results:
- Surgical IOP reduction was associated with prevention of visual field damage progression in NTG eyes.
- Higher preoperative IOP (P = 0.006) and absence of diabetes mellitus (P = 0.04) were significant predictors of better visual field prognosis.
- Functional outcomes in the lower IOP group were influenced by factors such as Ca2+-channel blocker use (P = 0.08) and the presence of disc hemorrhage (P = 0.02).
Conclusions:
- Both intraocular pressure (IOP)-related and independent factors play a role in the progression of visual field damage in normal-tension glaucoma (NTG).
- The functional prognosis for NTG eyes with low IOP is significantly influenced by IOP-unrelated factors, highlighting the complexity of disease management.