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[Value of a computer-assisted screening method (PAPNET) for the detection of infectious cervico-uterine smears]
M Bernier1, A M Bergemer, C Got
1Service d'Anatomie et de Cytologie Pathologiques, Hôpital A. Paré, Université Paris VI, Boulogne.
Archives D'Anatomie Et De Cytologie Pathologiques
|October 1, 1998
Summary
The PAPNET system, a computerized tool for cervical smear screening, showed low accuracy in detecting common infectious organisms in inflammatory samples. Its use as an exclusive pre-screening method requires careful consideration due to these limitations.
Area of Science:
- Gynecologic pathology
- Computational pathology
- Infectious disease diagnostics
Context:
- The PAPNET system, utilizing neuronal networks, is approved in the USA for cervical smear re-screening and quality assurance.
- Its efficacy in detecting infectious organisms, particularly in inflammatory cervico-uterine smears, has not been extensively studied.
Purpose:
- To evaluate the accuracy of the PAPNET system in identifying infectious organisms in inflammatory cervico-uterine smears.
- To assess the PAPNET system's performance in diagnosing specific infections like Trichomonas, mycoses, and Gardnerella.
Summary:
- The PAPNET system re-screened 42 inflammatory cervico-uterine smears, with high inter-observer agreement (39/42 cases).
- The system detected infectious organisms in only 66% of cases, with varying accuracy for specific pathogens: Trichomonas (63%), mycoses (56%), Gardnerella (87%). No herpetic lesions were identified.
Impact:
- The study highlights the PAPNET system's limited accuracy in diagnosing infectious cervico-uterine smears.
- Findings suggest caution when considering the PAPNET system as a sole pre-screening tool for infectious agents.
