[Functions of AT2 receptors of angiotensin II]

The structure, the coding gene and expression of the AT2 subtype receptor of angiotensin II have been described recently; however, the possible role of this receptor remains unclear despite its presence in most mammalian tissues. The AT2 receptor is probably involved in fetal growth and adult tissue repair and remodelling, especially in the cardiovascular system. There are still conflicting results, in vitro and in vivo, as to whether AT2 receptors limit and/or accelerate the growing processes in the cardiovascular tissues.