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[A metastatic neuroendocrine tumor with exceptional outcome!]
C Agard1, P Guerzider, J Bouillard
1Service de pneumologie, Centre Hospitalier, Saint-Nazaire, France.
Introduction:
Neuroendocrine tumors are rare, with poor prognosis when not or poorly differentiated.
Exegesis:
The authors report the case of a patient who presented with a metastatic poorly differentiated neuroendocrine tumor that was resistant to chemotherapy. The different sites of the carcinoma were lung, pancreas, kidney and lymph nodes. The patient received no treatment and complete spontaneous remission appeared after 21 months. This remission has been lasting for five years.
Conclusion:
It is the first case of spontaneous remission of a metastatic poorly differentiated neuroendocrine tumor. The evolution and classical sites of neuroendocrine tumors are reviewed. Renal metastasis is also unusual. This report illustrates the fact that neuroendocrine tumors are heterogeneous.