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Postimplantation density changes in coralline hydroxyapatite orbital implants

B S Sires1, J B Holds, C R Archer

  • 1Department of Ophthalmology, University of Washington, Seattle, USA.

Ophthalmic Plastic and Reconstructive Surgery
|October 23, 1998
PubMed
Summary
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Coralline hydroxyapatite orbital implants show significant mineral density increases post-implantation. This suggests no implant mineral resorption, indicating long-term stability for orbital implants.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Medical Imaging

Background:

  • Orbital implants are used to restore volume and support after eye removal.
  • Coralline hydroxyapatite is a biocompatible material used in orbital implants.
  • Understanding implant density changes is crucial for assessing long-term integration and stability.

Purpose of the Study:

  • To evaluate serial changes in mineral density of coralline hydroxyapatite orbital implants.
  • To assess the long-term stability and integration of these implants in the human socket.

Main Methods:

  • Prospective analysis of five patients receiving coralline hydroxyapatite orbital implants.
  • Quantitative computed tomography (QCT) used for mineral density measurements.
  • Measurements taken pre-implantation and at two postoperative intervals (3-8 months and 22-39 months).

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Main Results:

  • Orbital implant mineral density increased by an average of 135% within 3-8 months post-implantation.
  • A further average increase of 5% was observed between 22-39 months post-implantation.
  • One evisceration implant showed a decrease in density, while others demonstrated stability or continued increase, suggesting no significant mineral resorption.

Conclusions:

  • Coralline hydroxyapatite orbital implants exhibit a marked increase in mineral density after implantation.
  • Continued slight increases in density are observed up to 3 years post-implantation in most cases.
  • The findings suggest a lack of implant mineral resorption, supporting the use of coralline hydroxyapatite for orbital reconstruction.