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[Spontaneous and postoperative spondylodiscitis. A material concerning 23 patients]
S E Hansen1, E Gutschik, A Karle
1H:S Bispebjerg Hospital, reumatologisk afdeling H.
Ugeskrift for Laeger
|October 24, 1998
Summary
This study on spondylodiscitis found that antibiotics effectively treated bacterial infections, leading to symptom resolution. While clinical signs improved quickly, radiological changes persisted for months, highlighting the importance of prolonged antibiotic therapy.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Radiology
Background:
- Spondylodiscitis is a serious spinal infection.
- Prompt diagnosis and treatment are crucial for patient outcomes.
Purpose of the Study:
- To analyze clinical and microbiological findings in patients with spondylodiscitis.
- To evaluate treatment outcomes and identify causative microorganisms.
Main Methods:
- Retrospective analysis of 23 spondylodiscitis patients.
- Blood cultures and CT-guided spinal biopsies were performed.
- Microbiological identification and antibiotic susceptibility testing were conducted.
Main Results:
- Staphylococcus aureus was identified in acute spontaneous cases.
- Coagulase-negative staphylococci were common in post-operative infections.
- Antibiotic treatment (mean 5.1 months) led to symptom resolution and CRP normalization.
Conclusions:
- Antibiotic therapy is effective for bacterial spondylodiscitis.
- Radiological progression may continue despite clinical improvement.
- Early microbiological diagnosis aids targeted treatment.