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Related Experiment Videos

Psychiatric comorbidity in methadone maintained patients

B J Mason1, J H Kocsis, D Melia

  • 1Laboratory of the Biology of Addictive Diseases, Rockefeller University, New York, NY, USA.

Journal of Addictive Diseases
|October 28, 1998
PubMed
Summary

Diagnosing comorbid psychiatric disorders in methadone maintenance patients is crucial. Common conditions like depression and anxiety correlate with poorer treatment outcomes and increased challenges.

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Area of Science:

  • Psychiatry
  • Addiction Medicine
  • Clinical Psychology

Background:

  • Methadone maintenance therapy is a key treatment for opioid use disorder.
  • Comorbid psychiatric disorders are common in patients receiving methadone maintenance treatment.
  • Identifying these comorbidities can refine treatment strategies and improve patient outcomes.

Purpose of the Study:

  • To assess the prevalence of psychiatric disorders in methadone-maintained patients.
  • To investigate the relationship between psychiatric diagnoses and treatment outcomes.
  • To identify patient subgroups based on psychiatric comorbidities.

Main Methods:

  • A sample of 75 methadone maintenance patients (treatment >30 days) was evaluated.
  • Standardized assessments included the Addiction Severity Index, Global Assessment Scale, and Mini-Mental Status Exam.

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  • Psychiatric diagnoses were determined using the Diagnostic Interview Schedule for DSM-III-R criteria.

    • Main Results:

    • Psychiatric diagnoses were highly prevalent in the study sample.
    • The most common diagnoses included depression, phobic disorders, antisocial personality disorder, and generalized anxiety disorder.
    • Increased number of diagnoses and severity of psychopathology correlated with higher rates of concurrent drug abuse, family-social problems, and unemployment.

    Conclusions:

    • Comorbid psychiatric disorders are frequent among methadone-maintained patients.
    • The severity and number of psychiatric diagnoses are significant predictors of negative treatment outcomes.
    • Screening for and treating comorbid psychiatric conditions is essential for optimizing care in this population.