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[Toxic epidermal necrolysis after treatment with lamotrigine]
1Dermatologisk afdeling, Bispebjerg Hospital, København.
Ugeskrift for Laeger
|November 24, 1998
Abstract:
A case of toxic epidermal necrolysis following treatment with lamotrigine is presented. A 20 year old male suffering from epilepsy was treated with lamotrigine in addition to valproic acid. After three weeks he developed cutaneous manifestations of Steven-Johnson's syndrome followed by toxic epidermal necrolysis, mucosal lesions and liver symptoms. He was treated with systemic corticosteroids, antibiotics and intravenous fluid, and recovered after a few weeks.