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[Enteral nutrition in severe ulcerative colitis. Digestive tolerance and nutritional efficiency]
J Klaassen1, R Zapata, J G Mella
1Departamentos de Nutrición, Gastroenterología y Cirugía Digestiva, Facultad de Medicina, Pontificia Universidad Católica de Chile.
Revista Medica De Chile
|November 27, 1998
Summary
Total enteral nutrition is safe and well-tolerated for severe ulcerative colitis patients, showing improved prealbumin levels. This nutritional support offers a favorable anabolic effect, enhancing patient recovery.
Area of Science:
- Gastroenterology
- Clinical Nutrition
- Inflammatory Bowel Disease
Background:
- Traditional use of Total Parenteral Nutrition (TPN) in severe ulcerative colitis.
- Need for evaluating alternative nutritional support strategies.
- Focus on safety, efficiency, tolerance, and cost of enteral nutrition.
Purpose of the Study:
- To assess the safety and efficacy of total enteral nutrition in severe ulcerative colitis.
- To evaluate nutritional efficiency, patient tolerance, and associated costs.
- To compare enteral nutrition with traditional TPN in this patient group.
Main Methods:
- Prospective study design.
- Inclusion of severe ulcerative colitis patients after initial medical treatment.
- Daily titration of polymeric formula concentration and volume.
Main Results:
- 17 patients (mean age 36.8 years) included.
- 82.4% tolerance with enteral nutrition, achieving >80% caloric needs by day 4 in 11 patients.
- Significant prealbumin increase (p=0.002) from 11.1 to 22.7 mg/dl; albumin unchanged.
Conclusions:
- Total enteral nutrition is a safe and well-tolerated option for severe ulcerative colitis.
- Positive anabolic effect suggested by prealbumin level increase.
- Enteral nutrition offers a viable alternative to TPN for nutritional support.