Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid
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Abstract:
In vitro addition of stearoyl-CoA in 10,000 x g supernatant of rat livers, first enhanced the rate of omega-oxidation of free [1-14C] stearate, until a concentration of the acyl-CoA reached to the same level of that of the substrate. Further addition of stearoly-CoA decreased gradually the oxidation rate.