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Related Experiment Videos

Possible antibiotic-associated colitis in a dog

M D Willard1, B Berridge, A Braniecki

  • 1Department of Small Animal Medicine, College of Veterinary Medicine, Texas A&M University, College Station 77843, USA.

Journal of the American Veterinary Medical Association
|December 23, 1998
PubMed
Summary

Antibiotic-associated colitis can occur in dogs, leading to severe gastrointestinal issues. Early colonoscopy and fecal cultures are recommended for dogs with severe diarrhea during antibiotic treatment.

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Area of Science:

  • Veterinary Medicine
  • Gastroenterology
  • Microbiology

Background:

  • Renal disease management in canines.
  • Antibiotic therapy protocols in veterinary practice.
  • Understanding canine colonic physiology.

Observation:

  • A Poodle with renal disease developed severe colonic disease, including mucosal collapse and necrosis.
  • The colonic disease onset coincided with antibiotic administration.
  • Clinical signs included severe large-bowel diarrhea.

Findings:

  • Bacterial cultures revealed a disrupted colonic flora, with Streptococcus pyogenes, Pseudomonas aeruginosa, and Candida albicans predominating.
  • The condition was suggestive of antibiotic-associated colitis.
  • The case proved fatal, indicating the potential severity of this condition.

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Implications:

  • Colonoscopy is a valuable diagnostic tool for dogs with severe diarrhea linked to antibiotic use.
  • Nonselective bacterial fecal culture can aid in diagnosing dysbiosis during antibiotic treatment.
  • This case highlights the critical need for monitoring gastrointestinal health during antibiotic therapy in dogs.